A high school student named Yu Komori is bitten by a radioactive spider, which gave him spider-like powers. Yu faces Japanese versions of villains such as Electro, the Lizard and the Kangaroo. Yu also has an Aunt May (her name is "Mei"), and the publisher of the Joho newspaper is a counterpart to J. Jonah Jameson.

Only 7 out of the 13 Japanese stories in total were fully translated by Marvel, with heavy edits to remove the violent scenes. After that the title was cancelled, which was a likely decision by Marvel since the stories written by Hirai departed even further from the source material, and included scenes of sexual and gruesome imagery of a kind not seen in the original US Spider-Man comics.